s="" natural="" relations,="" loosened="" their="" responsibilities="" to="" kin="" and="" neighbors,="" （="" ）substituted="" superficial="" relationships="" with="" passing="" acquaintances.'>
Not too many years ago it seemed obvious both to the general public and to sociologists that modern society has changed people's natural relations, loosened their responsibilities to kin and neighbors, and （ ）substituted superficial relationships with passing acquaintances.
A.in their place for B.in its place for C.in their place D.in place
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